anti- Stathmin antibody
£245.00
anti- Stathmin antibody (FNab08311)
Product
| Cat # FNab08311 | Size 100µg |
Price
£245.00
|
Qty
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Description
Stathmin 1(STMN1) normally regulates microtubule dynamics either by sequestering free tubulin heterodimers or by promoting microtubule catastrophe. STMN1 is highly expressed in fetal and adult brain, spinal cord, and cerebellum. Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. Phosphorylation of stathmin is involved in response to NGF, neuron polarization and microtubule polymerization inhibition activity. Increased expression of STMN1 has been observed in a variety of human malignancies, such as colorectal primary tumors and metastatic tissues, but its association with melanoma is so far not well known.
Specifications
| Product Size | 100µg |
|---|---|
| Antibody Type | Monoclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Protein A+G purification |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Mouse |
| Isotype | IgG2a |
| Immunogen | stathmin 1/oncoprotein 18 |
| Alternate Names | C1orf215, FLJ32206, Lag, LAP18, Metablastin, Oncoprotein 18, OP18, Phosphoprotein p19, PP17, PP19, PR22, Prosolin, Protein Pr22, SMN, Stathmin, stathmin 1/oncoprotein 18, Stathmin1, STMN1 |
| Calculated MW | 18 kDa |
| Protein ID | P16949 |
| Clone | 9F7 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IF, IHC, WB |
| Recommended dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200 |