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SAFB antibody

£245.00

SAFB antibody (FNab07578)

Product

Cat #  FNab07578 Size  100ug Price 
£245.00
Qty 

Description

Binds to scaffold/matrix attachment region(S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex(consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing(By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter(By similarity). Can inhibit cell proliferation.

Specifications

Manufacturer Cat# FNab07578
Product Size 100ug
Antibody Type Polyclonal
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Physical Appearance liquid
Purification Immunogen affinity purified
Purity ≥95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Immunogen scaffold attachment factor B
Alternate Names Scaffold attachment factor B1 (SAF-B, SAF-B1)|HSP27 estrogen response element-TATA box-binding protein (HSP27 ERE-TATA-binding protein)|SAFB|HAP|HET|SAFB1
Calculated MW 150 kDa
Protein ID Q15424
Reactivity Human
Applications ELISA, IF, IHC, WB
Recommended dilution WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Gene ID 6294