Anti-Ross River Virus (Clone: RRV-12)
Anti-Ross River Virus (Clone: RRV-12) (LT574-GRP)
Products
Description
Ross River Virus (RRV) is a mosquito-borne, positive sense, single-stranded virus endemic to Australia and Papua New Guinea that belongs to the arthritogenic group of alphaviruses1. The mature glycoprotein is composed of E1 and E2 envelope proteins in a heterodimer, expressed as a trimeric spike on the virus surface 2.
B cells were transformed with Epstein-Barr virus and then screened by direct virus binding ELISA. Hybridoma lines were established and mAbs were purified by single-cell flow cytometric sorting.
Clone RRV-12 is of the IgG1 isotype and is capable of binding and incompletely neutralizing prototype strain RRV T48 in a focus reduction neutralization test1.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | LT574 |
| Concentration | ≥1.0 mg/ml |
| Formulation | This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Clone | RRV-12 |
| Target | Ross River Virus |
| Applications | ELISA, N |
| Antigen | RoE2 is expressed on the surface of RRV. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one year. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≥ -70°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | Ross River Virus |