Anti-Rat IL-18 (Clone 69604)
£581.25
Anti-Rat IL-18 (Clone 69604) (I-675-500ug)
Product
| Cat # I-675-500ug | Size 500 µg |
Price
£581.25
|
Qty
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Description
Interleukin-18 is a member of the interleukin-1 family of cytokines with pro-inflammatory and tumor-suppressive properties. Its ability to potently enhance the production of interferon-gamma indicates in particular the crucial function of interleukin-18 as an immunomodulatory molecule. In fact, high levels of interleukin-18 are detected in human diseases associated with immunoactivation including viral or bacterial infections and chronic inflammation. Animal models suggest suppression of interleukin-18 bioactivity as a novel therapeutic concept specifically for the treatment of chronic inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis. It is the only cytokine with a unique capacity to induce T helper 1 or T helper 2 polarization, depending on the immunologic context.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-675 |
| Product Size | 500 µg |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Interleukin-18 IL-1F4 69604 IL-18 Rat Anti-Rat IL-18 |
| Isotype | IgG1 |
| Clone | 69604 |
| Target | IL-18 |
| Antibody Type | Monoclonal |
| Applications | WB |
| Storage | -20°C to -70°C |
| Protein | IL-18 |