Anti-Quinidine Antibody (16501)
Anti-Quinidine Antibody (16501) (16501-GRP)
Products
Description
Quinidine is a class I antiarrhythmic agent. Like all other class I antiarrhythmic agents, quinidine primarily works by blocking the fast inward sodium current (INa) which causes the phase 0 depolarization of the cardiac action potential to decrease (decreased Vmax). Quinidine also blocks the slowly inactivating, tetrodotoxin-sensitive Na current, the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito. At micromolar concentrations, quinidine inhibits Na /K -ATPase by binding to the same receptor sites as the digitalis glycosides such as ouabain.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | 16501 |
| Concentration | Lot Specific |
| Formulation | This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added. |
| Clone | QD11-228.6.5 |
| Target | Quinidine |
| Applications | ELISA |
| Storage | This antibody is stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles. |
| Protein | Quinidine |