Anti-PTEN (Phospho-Ser380/Thr382/Thr83) Antibody (43056)
£398.44
Anti-PTEN (Phospho-Ser380/Thr382/Thr83) Antibody (43056) (43056-100ul)
Product
| Cat # 43056-100ul | Size 100μl |
Price
£398.44
|
Qty
|
Description
Phosphatase and tensin homolog (PTEN) was identified as a tumor suppressor that is mutated in many cancers. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin-like domain as well as a catalytic domain similar to the dual specificity protein tyrosine phosphatases. Unlike most protein tyrosine phosphatases, PTEN preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol- 3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating Akt/PKB signaling pathway.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | 43056 |
| Product Size | 100μl |
| Concentration | 1.0 mg/ml |
| Formulation | PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Target | PTEN (Phospho-Ser380/Thr382/Thr83) |
| Applications | IF, IHC, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. |