Anti-Prekallikrein Heavy Chain [Clone 13G11]
£609.38
Anti-Prekallikrein Heavy Chain [Clone 13G11] (19901-200ug)
Product
| Cat # 19901-200ug | Size 200 µg |
Price
£609.38
|
Qty
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Description
Human prekallikrein, a serine protease zymogen, is present in plasma as two variants, 88kDa and 85kDa, probably due to different carbohydrate content. Approximately 75% of the total prekallikrein in plasma is noncovalently associated with high molecular weight kininogen (HMWK). HMWK mediates binding of prekallikrein to a negatively-charged surface which is required for its optimal activation to kallikrein by activated factor XII. Although kallikrein light and heavy chains can behave as functionally independent domains, the interaction between these two chains is essential for full biologic activity.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | 19901 |
| Product Size | 200 µg |
| Concentration | Lot Specific |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Clone | 13G11 |
| Target | Prekallikrein Heavy Chain |
| Applications | ELISA, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. |