anti- Phospho-AMPKA1(T183)/AMPKA2(T172) antibody
£245.00
anti- Phospho-AMPKA1(T183)/AMPKA2(T172) antibody (FNab10153)
Product
| Cat # FNab10153 | Size 100µg |
Price
£245.00
|
Qty
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Description
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Specifications
| Product Size | 100µg |
|---|---|
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Phospho-AMPKα-T172 |
| Alternate Names | AMPK, AMPKa1 |
| Calculated MW | 64kDa |
| Protein ID | Q13131/P54646 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Gene ID | 5562/5563 |