NUDT3 antibody
£245.00
NUDT3 antibody (FNab05905)
Product
| Cat # FNab05905 | Size 100ug |
Price
£245.00
|
Qty
|
Description
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5(diphosphoinositol pentakisphosphate) and [PP]2-InsP4(bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6(inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Specifications
| Manufacturer Cat# | FNab05905 |
|---|---|
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | nudix(nucleoside diphosphate linked moiety X)-type motif 3 |
| Alternate Names | Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1)|Diadenosine hexaphosphate hydrolase (Ap6A hydrolase)|Endopolyphosphatase|Nucleoside diphosphate-linked moiety X motif 3 (Nudix motif 3)|m7GpppN-mRNA hydrolase|m7GpppX diphosphatase|NUDT3|DIPP|DIPP1 |
| Calculated MW | 20-30 kDa |
| Protein ID | O95989 |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Recommended dilution | WB: 1:500-1:2000 |
| Gene ID | 11165 |