anti- NCOA6 antibody
£227.50
anti- NCOA6 antibody (FNab05591)
Product
| Cat # FNab05591 | Size 100µg |
Price
£227.50
|
Qty
|
Description
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist-and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids(GR and ERs), retinoids(RARs and RXRs), thyroid hormone(TRs), vitamin D3(VDR) and prostanoids(PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.
Specifications
| Product Size | 100µg |
|---|---|
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | nuclear receptor coactivator 6 |
| Alternate Names | AIB3, KIAA0181, RAP250, TRBP |
| Calculated MW | 68 kDa ; 219 kDa ; 110 kDa |
| Protein ID | Q14686 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IP |
| Recommended dilution | IP: 1:200-1:2000 |
| Gene ID | 23054 |