Anti-Nav1.7 Na+ Channel Antibody (11517) (11517-100ug)

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Nav1.7 is a voltage-gated sodium channel that plays an important role in the generation and conduction of action potentials making it important for electrical signaling by most excitable cells. Since Nav1.7 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.7 will not directly affect those cells.