Anti-Mouse TCR β chain (TCR) - Purified (PhenoCyler-Fusion (CODEX)® Ready)
£89.06
Anti-Mouse TCR β chain (TCR) - Purified (PhenoCyler-Fusion (CODEX)® Ready) (T900-50ug)
Product
| Cat # T900-50ug | Size 50 µg |
Price
£89.06
|
Qty
|
Description
TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells1. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond2. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling3,4. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival5,6.
Specifications
| Manufacturer Cat# | T900 |
|---|---|
| Product Size | 50 µg |
| Concentration | 0.5 mg/ml |
| Formulation | This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4. |
| Clone | H57-597 |
| Target | TCR beta |
| Applications | IHC FF, PhenoCycler® |
| Antigen | TCRβ is expressed on αβ thymocytes, peripheral T cells, and NKT cells. |
| Storage | This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Protein | TCR beta |