Anti-Mouse TCR β chain - DyLight® 550
Anti-Mouse TCR β chain - DyLight® 550 (T669-GRP)
Products
Description
TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells1. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond2. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling3,4. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival5,6.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | T669 |
| Concentration | 0.2 mg/ml |
| Formulation | This DyLight® 550 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Isotype | IgG |
| Clone | H57-597 |
| Target | TCR beta |
| Antibody Type | Monoclonal |
| Applications | FC, IHC FF |
| Antigen | TCRβ is expressed on αβ thymocytes, peripheral T cells, and NKT cells. |
| Storage | This DyLight® 550 conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | TCR beta |