Anti-Mouse/Rat CD71 - APC
Anti-Mouse/Rat CD71 - APC (C869-GRP)
Products
Description
CD71 is a transferrin receptor on the cell surface that mediates the uptake of transferrin-iron complexes, thereby mediating cellular proliferation1. CD71 is a homodimeric glycoprotein containing 760 amino acids and it binds to diferric transferrin2. Binding by diferric transfferin causes CD71 to be internalized, and diferric iron is subsequently released3. CD71 is highly expressed on malignant cells, as iron uptake is necessary for aberrant cell proliferation4.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C869 |
| Concentration | 0.2 mg/ml |
| Formulation | This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Clone | OX-26 |
| Target | CD71 |
| Applications | FC |
| Antigen | CD71 is expressed on the surface of proliferating cells, reticulocytes, and erythroid precursors. |
| Storage | This Allophycocyanin (APC) conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | CD71 |