Anti-Mouse MAdCAM-1 (MECA-367) - DyLight® 488
Anti-Mouse MAdCAM-1 (MECA-367) - DyLight® 488 (M1406-GRP)
Products
Description
Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a multifunctional type l transmembrane adhesion molecule that is expressed selectively at venular sites of lymphocyte extravasation into mucosal lymphoid tissues and lamina propria, where it directs local lymphocyte trafficking.1 MAdCAM-1 is involved in the normal recirculation of lymphocytes between the blood and the gastrointestinal tract.2 MAdCAM-1 may be a relevant tissue-specific therapeutic target for the modulation of inflammatory bowel disease activity.3
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | M1406 |
| Concentration | 0.2 mg/ml |
| Formulation | This DyLight® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody MAdCAM-1 MECA-367 Mouse Anti-Mouse MAdCAM-1 - DyLight® 488 |
| Isotype | IgG2a |
| Clone | MECA-367 |
| Target | MADCAM-1 |
| Antibody Type | Monoclonal |
| Applications | FC |
| Storage | This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | MADCAM-1 |