Anti-Mouse/Human IL-5 - Purified
Anti-Mouse/Human IL-5 - Purified (I-1038-GRP)
Products
Description
IL-5 is a 26 kD TH2 cytokine and a homodimeric glycoprotein that is part of the hematopoietic family. IL-5 stimulates B cell growth as well as increases Ig secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a major regulator of eosinophil accumulation in tissues. In fact, in Hodgkin lymphoma, the characteristically observed eosinophilia is suspected to result from an increased production of IL-5. IL-5 may also be the cause of several allergic diseases including asthma, where it is thought that eosinophils have a significant role in the disease pathology. There are several mAbs currently in use that target IL-5 for the treatment of severe eosinophilic asthma.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-1038 |
| Concentration | 0.5 mg/ml |
| Formulation | This Purified conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody Interleukin-5 EDF BCDFII TRF TRFK5 IL-5 Mouse Anti-Mouse/Human IL-5 - Purified |
| Isotype | IgG1 |
| Clone | TRFK5 |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, IHC FF, IHC FFPE, WB |
| Storage | This Purified conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | IL-5 |