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Anti-Mouse IL-4 R (Clone 129801)

Anti-Mouse IL-4 R (Clone 129801) (I-676-GRP)

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Description

IL-4 can signal through type I and type II receptor complexes, which share a common gamma chain. The type I receptor contains in addition to the gamma chain an IL-4R alpha subunit, whereas the type II receptor contains the IL-13R alpha. The secreted extracellular domain of IL-4R alpha, called sIL-4R alpha, binds IL-4 and antagonizes its activity. It plays an important role in regulating the differentiation of naive CD4+ T cells and class switching to IgG1 and IgE.

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# I-676
Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Alternate Names Monoclonal Antibody Interleukin-4 Receptor CD124 129801 IL-4 R Mouse Anti-Mouse IL-4 R
Isotype IgG2b
Clone 129801
Antibody Type Monoclonal
Applications ELISA Indirect, WB
Storage -20°C to -70°C
Protein IL-4 R