Anti-Mouse IL-4 (Clone 11B11) - Purified <i>in vivo</i> PLATINUMâ„¢ Functional Grade
£234.38
Anti-Mouse IL-4 (Clone 11B11) - Purified <i>in vivo</i> PLATINUMâ„¢ Functional Grade (I-2070-1mg)
Product
| Cat # I-2070-1mg | Size 1 mg |
Price
£234.38
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Qty
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Description
IL-4 antibody, 11B11, recognizes mouse IL-4, also known as B-cell differentiation factor (BCDF) and B-cell stimulatory factor (BSF1). IL-4 is a pleiotropic 20 kDa cytokine secreted by T helper 2 cells (Th2) cells, natural killer T (NKT) cells, mast cells, eosinophils, and basophils1,2. IL-4 signaling through the IL-4 receptor alpha chain (IL-4Ra) induces the differentiation of naive T cells to Th2 cells3,4 and stimulates B cell differentiation, proliferation, and class switching to IgG1 and IgE isotypes5. In addition, IL-4 is implicated in normal wound healing6,7 and airway inflammation in patients with asthma8.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-2070 |
| Product Size | 1 mg |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Clone | 11B11 |
| Target | IL-4 |
| Applications | CyTOF®, ELISA Cap, ELISPOT, FA, ICC, IHC, in vivo, IP, N |
| Antigen | IL-4 is secreted by Th2 cells, NKT cells, mast cells, eosinophils, and basophils. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | IL-4 |