Anti-Mouse IL-4 (Clone 11B11) - DyLight® 488
£276.56
Anti-Mouse IL-4 (Clone 11B11) - DyLight® 488 (I-1077-100ug)
Product
| Cat # I-1077-100ug | Size 100 µg |
Price
£276.56
|
Qty
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Description
IL-4 antibody, 11B11, recognizes mouse IL-4, also known as B-cell differentiation factor (BCDF) and B-cell stimulatory factor (BSF1). IL-4 is a pleiotropic 20 kDa cytokine secreted by T helper 2 cells (Th2) cells, natural killer T (NKT) cells, mast cells, eosinophils, and basophils1,2. IL-4 signaling through the IL-4 receptor alpha chain (IL-4Ra) induces the differentiation of naive T cells to Th2 cells3,4 and stimulates B cell differentiation, proliferation, and class switching to IgG1 and IgE isotypes5. In addition, IL-4 is implicated in normal wound healing6,7 and airway inflammation in patients with asthma8.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-1077 |
| Product Size | 100 µg |
| Concentration | 0.2 mg/ml |
| Formulation | This DyLight® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody Interleukin-4 BCGF BCDF B Cell Stimulating Factor BSF-1 11B11 IL-4 Mouse Anti-Mouse IL-4 - Purified HCGF MCGF-2 MFF TCGF-2 lymphoid cell growth factor lymphoid mast basophils T helper subset development ELISA ELISPOT Flow Cytometry DyLight 488 |
| Isotype | IgG1 κ |
| Clone | 11B11 |
| Target | IL-4 |
| Antibody Type | Monoclonal |
| Applications | ICFC |
| Antigen | IL-4 is secreted by Th2 cells, NKT cells, mast cells, eosinophils, and basophils. |
| Storage | This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | IL-4 |