Anti-Mouse IL-2 (Clone JES6-5H4) - PE
£231.56
Anti-Mouse IL-2 (Clone JES6-5H4) - PE (I-1096-100ug)
Product
| Cat # I-1096-100ug | Size 100 µg |
Price
£231.56
|
Qty
|
Description
IL-2 is a 17.2 kD cytokine signaling protein that is the regulator of the proliferative and suppressive phases of the immune response, and stimulates growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes. It functions as a primary regulator of T cell homeostasis. Il-2 regulates the activities of white blood cells and plays a role in the immune system via “self” and “non-self” discrimination. IL-2 is a prime candidate in immunotherapeutics for both increasing T cell levels/function and for augmenting vaccine-elicited viral-specific T cell responses. IL-2 signal can be transduced via 3 different signaling pathways that include the JAK-STAT, PI3K/Akt/mTOR and MAPK/ERK pathways. Aldesleukin is a form of recombinant interleukin-2 for the treatment of cancers including malignant melanoma and renal cell cancer. Furthermore, there is additional therapeutic potential for IL-2 mAb use with transplants and autoimmune disease.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-1096 |
| Product Size | 100 µg |
| Concentration | 0.2 mg/ml |
| Formulation | This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody Interleukin-2 TCGF Lymphokine T-Cell Growth Factor Aldesleukin JES6-1A12 IL-2 Mouse Anti-Mouse IL-2 EDF KHF MAF-C1 TDF Flow Cytometry PE IL2 R-PE |
| Isotype | IgG2a κ |
| Clone | JES6-5H4 |
| Target | IL-2 |
| Antibody Type | Monoclonal |
| Applications | FC |
| Storage | This R-PE conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | IL-2 |