Anti-Mouse IL-18 Rα
Anti-Mouse IL-18 Rα (I-624-GRP)
Products
Description
The interleukin-18 receptor 1 (IL-18R1) is a cytokine receptor of the immunoglobulin superfamily. IL18R1 is also known as IL-18Rα, CDw218a (cluster of differentiation w218a), IL-1Rrp, and IL-1R family member. IL-18R1 specifically binds to interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IL-18Rα is expressed on Th1 cells, NK cell subset, neutrophils and IL-12-stimulated tonsillar B cells. By itself, IL-18Rα binds IL-18 with low affinity and when complexed with IL-18Rβ chain binds IL-18 with high affinity. The proinflammatory cytokine IL-18 and its receptor complex play an important role in the innate and autoimmune responses.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-624 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Interleukin-18 Receptor Alpha IL18R1 CDw218a IL-1Rrp IL1RRP IL-18Rα 112614 IL-18 Rα Mouse Anti-Mouse IL-18 Rα |
| Isotype | IgG1 |
| Clone | 112614 |
| Antibody Type | Monoclonal |
| Applications | ELISA Indirect, FC, WB |
| Storage | -20°C to -70°C |
| Protein | IL-18 R alpha |