Anti-Mouse IL-13 [Clone 38213]
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Anti-Mouse IL-13 [Clone 38213] (I-665-500ug)
Product
Description
Interleukin 13 (IL-13) is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells1, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα), which is also a component of the IL-4 receptor, and at least one of two known IL-13-specific binding chains.1 The functions of IL-13 overlap considerably with those of IL-4. Although IL-13 is associated primarily with the induction of airway disease, it also has anti-inflammatory properties. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-665 |
| Product Size | 500 µg |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Interleukin-13 ALRH BHR1 MGC116786 P600 NC30 38213 IL-13 Mouse Anti-Mouse IL-13 |
| Isotype | IgG2a |
| Clone | 38213 |
| Target | IL-13 |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, N, WB |
| Storage | -20°C to -70°C |
| Protein | IL-13 |