Anti-Mouse IL-1 R1, Type 1 - PE
Anti-Mouse IL-1 R1, Type 1 - PE (I-433-GRP)
Products
Description
IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1α and IL-1ß exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1α and IL-1ß, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-433 |
| Concentration | 0.2 mg/ml |
| Formulation | This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody Interleukin-1 R1 Interleukin-1 R1 JAMA-147 IL-1 R1 Mouse Anti-Mouse IL-1 R1 Type 1-R-Phycoerythrin |
| Isotype | IgG |
| Clone | JAMA-147 |
| Antibody Type | Monoclonal |
| Applications | FC |
| Antigen | T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells, neural cells |
| Storage | This R-PE conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | Interleukin-1 R1 |