Anti-Mouse IgD (Clone 11-26c.2a) - Purified No Carrier Protein (I-1410-GRP)

Immunoglobulin D (IgD) is one of the five main classes of immunoglobulins. Though it is an antibody that is not well understood, it has been discovered to have a vital role in both innate and adaptive immunity. It aids in activating and regulating B cells, especially in the upper respiratory mucosa. In this location, it enhances immune surveillance and defense against respiratory pathogens1. IgD also helps maintain a healthy microbiome by equipping myeloid effector cells with IgD antibodies that react to mucosal antigens, including both commensal and pathogenic microbes2. The 11-26c.2a clone is an essential tool in immunology research, particularly in the study of B cell development and activation pathways. It is widely used in flow cytometric analysis to identify surface IgD expression on mouse B cells. This provides valuable insights into B cell populations and their roles in immune responses3,4. When the antibody is conjugated, it allows for easy detection and multiplexing in flow cytometry, enabling comprehensive immunophenotyping studies5,6.