Anti-Mouse IFNβ - Purified <i>in vivo </i>GOLD™ Functional Grade
£1,710.94
Anti-Mouse IFNβ - Purified <i>in vivo </i>GOLD™ Functional Grade (I-439-50mg)
Product
| Cat # I-439-50mg | Size 50 mg |
Price
£1,710.94
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Qty
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Description
Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-α proteins and a single IFN-ß protein. The second class, type II IFN, consists of a single protein, IFN-γ. IFN-α and IFN-ß signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-ß has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-ß’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-439 |
| Product Size | 50 mg |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Alternate Names | Monoclonal Antibody IFNβ Inteferon Beta MIB-5E9.1 Mouse Anti-Mouse Interferon Beta (IFNβ) Low Endotoxin Functional Formulation Hamster PIP in vivo Low endotoxin MIB 5e9 5e9.1 |
| Isotype | IgG |
| Clone | MIB-5E9.1 |
| Target | IFNβ |
| Antibody Type | Monoclonal |
| Applications | in vivo, N, WB |
| Antigen | Fibroblasts & epithelial cells |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | IFNβ |