Anti-Mouse IFNAR-1 - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade
£1,490.63
Anti-Mouse IFNAR-1 - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade (I-1188-25mg)
Product
| Cat # I-1188-25mg | Size 25 mg |
Price
£1,490.63
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Qty
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Description
IFNAR1 is a type I membrane protein, that in conjunction with IFNAR2, makes up the heterodimeric receptor that binds all type I IFNs, which includes IFN α and β. Binding and activation of the receptor stimulates Janus protein kinases, which leads to the phosphorylation of several other proteins, namely STAT1 and STAT2. IFNAR1 has also been shown to interact with PRMT1 and Tyrosine kinase 2. Type I IFNs are a family of cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor and autoimmune responses In vivo.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-1188 |
| Product Size | 25 mg |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Alternate Names | Monoclonal Antibody IFNAR1 CD118 Ifar Ifnar Ifrc INF-a receptor Interferon-α/β receptor α chain MAR1-5A3 Mouse IFNAR1 IFN-αR1 IFN-α/β Receptor Subunit 1 |
| Isotype | IgG1 |
| Clone | MAR1-5A3 |
| Target | IFNAR1 |
| Antibody Type | Monoclonal |
| Applications | B, ELISA, FC, in vivo, IP, WB |
| Antigen | IFNAR1 and IFNAR2 are coexpressed on nearly all cells. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | IFNAR1 |