Anti-Mouse ICOS (Clone C398.4A) - Purified (PhenoCyler-Fusion (CODEX)® Ready)
£89.06
Anti-Mouse ICOS (Clone C398.4A) - Purified (PhenoCyler-Fusion (CODEX)® Ready) (I-2012-50ug)
Product
| Cat # I-2012-50ug | Size 50 µg |
Price
£89.06
|
Qty
|
Description
CD278 (ICOS) belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers (47-57kD) and enhances all basic T cell responses to a foreign antigen, specifically proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B cells. ICOS signaling is also an important regulator for T cell homeostasis. ICOS plays a role in humoral immune response and is thought to have involvement in the development of Th2 cells and to play a protective role in inflammatory autoimmune diseases.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-2012 |
| Product Size | 50 µg |
| Concentration | 0.5 mg/ml |
| Formulation | This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4. |
| Clone | C398.4A |
| Target | ICOS |
| Applications | IHC FF, PhenoCycler® |
| Antigen | ICOS is expressed on activated T cells and APCs including splenic B cells, dendritic cells, and macrophages. |
| Storage | This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Protein | ICOS |