Anti-Mouse ICAM-1 (CD54) (Clone BE29G1) - Purified <i>in vivo </i>GOLDâ„¢ Functional Grade
Anti-Mouse ICAM-1 (CD54) (Clone BE29G1) - Purified <i>in vivo </i>GOLDâ„¢ Functional Grade (C391-GRP)
Products
Description
Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein1 and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines.2 ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.3
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C391 |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Alternate Names | Monoclonal Antibody Inter-Cellular Adhesion Molecule 1 BB2 CD54 P3.58 BE29G1 ICAM-1 Mouse Anti-Mouse ICAM-1 Low Endotoxin Functional Formulation |
| Isotype | IgG2a |
| Clone | BE29G1 |
| Antibody Type | Monoclonal |
| Applications | B, IP, WB |
| Antigen | The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | Inter-Cellular Adhesion Molecule 1 |