Anti-Mouse/Human Interleukin-5 (IL-5) - PE
£100.31
Anti-Mouse/Human Interleukin-5 (IL-5) - PE (I-1064-25ug)
Product
| Cat # I-1064-25ug | Size 25 µg |
Price
£100.31
|
Qty
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Description
IL-5 is a 26 kD TH2 cytokine and a homodimeric glycoprotein that is part of the hematopoietic family. IL-5 stimulates B cell growth as well as increases Ig secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a major regulator of eosinophil accumulation in tissues. In fact, in Hodgkin lymphoma, the characteristically observed eosinophilia is suspected to result from an increased production of IL-5. IL-5 may also be the cause of several allergic diseases including asthma, where it is thought that eosinophils have a significant role in the disease pathology. There are several mAbs currently in use that target IL-5 for the treatment of severe eosinophilic asthma.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-1064 |
| Product Size | 25 µg |
| Concentration | 0.2 mg/ml |
| Formulation | This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody Interleukin-5 Eosinophil differentiation factor (EDF) Eosinophil colony stimulating factor (Eo-CSF) B cell growth factor-2 (BCGF-2) B cell differentiation factor for IgM (BCDF-m) IgA enhancing factor (IgA-EF) T-cell replacing factor-1 (TRF-1) TRFK5 IL-5 Mouse IL5 PE |
| Isotype | IgG1 κ |
| Clone | TRFK5 |
| Target | IL-5 |
| Antibody Type | Monoclonal |
| Applications | FC, ICC |
| Antigen | Mast cells, T cells, eosinophils |
| Storage | This R-PE conjugated antibody is stable when stored at 2-8°C. Do not freeze. |
| Protein | IL-5 |