Anti-Mouse/Human IL-5 - Purified <i>in vivo</i> GOLDâ„¢ Functional Grade
£1,392.19
Anti-Mouse/Human IL-5 - Purified <i>in vivo</i> GOLDâ„¢ Functional Grade (I-1060-25mg)
Product
| Cat # I-1060-25mg | Size 25 mg |
Price
£1,392.19
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Qty
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Description
IL-5 is a 26 kD TH2 cytokine and a homodimeric glycoprotein that is part of the hematopoietic family. IL-5 stimulates B cell growth as well as increases Ig secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a major regulator of eosinophil accumulation in tissues. In fact, in Hodgkin lymphoma, the characteristically observed eosinophilia is suspected to result from an increased production of IL-5. IL-5 may also be the cause of several allergic diseases including asthma, where it is thought that eosinophils have a significant role in the disease pathology. There are several mAbs currently in use that target IL-5 for the treatment of severe eosinophilic asthma.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-1060 |
| Product Size | 25 mg |
| Concentration | ≥ 2.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Clone | TRFK5 |
| Target | IL-5 |
| Applications | CyTOF®, Depletion, ELISA Cap, ELISPOT, FA, FC, IHC FFPE, in vivo, N, WB |
| Antigen | Mast cells, T cells, eosinophils |
| Storage | This Low Endotoxin Functional Formulation, GOLD Antibody is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | IL-5 |