Anti-Mouse CTLA-4 (CD152) - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade
Anti-Mouse CTLA-4 (CD152) - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade (C2444-GRP)
Products
Description
CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C2444 |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Alternate Names | Monoclonal Antibody CD152 CTLA-4 UC10-4F10-11 Mouse CD152 Anti-Mouse CD152 Mouse CTLA-4 Clone UC10-4F10-11 |
| Isotype | IgG1 |
| Clone | UC10-4F10-11 |
| Target | CTLA-4 |
| Antibody Type | Monoclonal |
| Applications | FA, FC, in vivo, IP, WB |
| Antigen | CTLA-4 is expressed on activated T and B lymphocytes. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CTLA-4 |