Anti-Mouse CD86 - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade
Anti-Mouse CD86 - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade (C6158-GRP)
Products
Description
CD86 is an 80kD Ig superfamily member that is involved in immunoglobulin class-switching and activation of NK cell-mediated cytotoxicity. CD80 is closely related to, and works in tandem with CD86 to prime T- cells. CD86 is expressed earlier in the immune response than CD80. The ligation of CD28 on T cells with CD80 and CD86 on APCs co-stimulates T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD86 can also bind to CTLA-4 to deliver an inhibitory signal to T cells.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C6158 |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Isotype | IgG2a κ |
| Clone | GL1 |
| Target | B7-2 |
| Applications | B, ELISA, FC, IHC FF, in vivo, IP, WB |
| Antigen | CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | B7-2 |