Anti-Mouse CD86 - APC
Anti-Mouse CD86 - APC (C2161-GRP)
Products
Description
CD86 is an 80kD Ig superfamily member that is involved in immunoglobulin class-switching and activation of NK cell-mediated cytotoxicity. CD80 is closely related to, and works in tandem with CD86 to prime T- cells. CD86 is expressed earlier in the immune response than CD80. The ligation of CD28 on T cells with CD80 and CD86 on APCs co-stimulates T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD86 can also bind to CTLA-4 to deliver an inhibitory signal to T cells.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C2161 |
| Concentration | 0.2 mg/ml |
| Formulation | This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody CD86 B7-2 B70 Ly-58 CD-86 GL1 Mouse Anti-Mouse CD86 (B7-2) - APC APC Flow Cytometry Immunology |
| Isotype | IgG2a κ |
| Clone | GL1 |
| Target | B7-2 |
| Antibody Type | Monoclonal |
| Applications | FC |
| Antigen | CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. |
| Storage | This APC conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | B7-2 |