Anti-Mouse CD70 (Clone FR70) - Purified <i>In vivo </i>GOLDâ„¢ Functional Grade
£614.06
Anti-Mouse CD70 (Clone FR70) - Purified <i>In vivo </i>GOLDâ„¢ Functional Grade (C2402-0.5mg)
Product
| Cat # C2402-0.5mg | Size 0.5 mg |
Price
£614.06
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Qty
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Description
CD70 is a 30-33 kD type II transmembrane glycoprotein and a member of the TNF superfamily. CD70 is the ligand for CD27; the binding of which delivers costimulatory signals to T cells and NK cells. CD70 is expressed on highly activated lymphocytes characteristic of T- and B-cell lymphomas. Because normal lymphocytes have low CD70 expression, it has been suggested that anti-CD70 antibodies may be a possible treatment for CD70 positive lymphomas. CD70-specific antibodies are currently under investigation for the treatment of hematological malignancies and renal cell carcinoma.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C2402 |
| Product Size | 0.5 mg |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Alternate Names | Monoclonal Antibody CD70 TNFSF7 KI-24 antigen CD27 Ligand CD27L FR70 Mouse Anti-Mouse CD70 - Purified Low Endotoxin Functional Formulation |
| Isotype | IgG2b κ |
| Clone | FR70 |
| Antibody Type | Monoclonal |
| Applications | FA, FC, WB |
| Antigen | CD70 is expressed by highly activated lymphocytes as found in T-cell and B-cell lymphomas. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD70 |