Anti-Mouse CD62L - DyLight® 488
Anti-Mouse CD62L - DyLight® 488 (C2095-GRP)
Products
Description
CD62L is a 75-95 kD glycoprotein which is also known as L-selectin, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte "rolling" on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C2095 |
| Concentration | 0.2 mg/ml |
| Formulation | This DyLight® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody CD62L L-Selectin Leu-8 MEL-14 Mouse Anti-Mouse CD62L - DyLight® 488 |
| Isotype | IgG2a |
| Clone | MEL-14 |
| Target | CD62L |
| Antibody Type | Monoclonal |
| Applications | FA, FC |
| Storage | This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | CD62L |