Anti-Mouse CD54 (ICAM-1) (Clone YN1/1.7.4) - Purified (PhenoCyler-Fusion (CODEX)® Ready)
£89.06
Anti-Mouse CD54 (ICAM-1) (Clone YN1/1.7.4) - Purified (PhenoCyler-Fusion (CODEX)® Ready) (C527-50ug)
Product
| Cat # C527-50ug | Size 50 µg |
Price
£89.06
|
Qty
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Description
ICAM-1 is a 55 kDa glycoprotein that is part of the Ig superfamily. It is heavily glycosylated to form 75 kDa to 115 kDa. ICAM-1 is known to be an adhesion and viral entry molecule, and its long suspected involevement in signal transduction is being elucidated. The signal-transducing functions of ICAM-1 appear to be mainly associated with proinflammatory pathways. Furthermore, ICAM-1 signaling appears to act as a beacon for inflammatory immune cells such as macrophages and granulocytes bringing about inflammation via lymphocyte trafficking. ICAM-1 is essential for the transmigration of leukocytes out of blood vessels and into tissues, and is a marker of endothelial dysfunction leading to damaging vascular disorders in umbilical and placental vascular tissue of gestational pregnancies. ICAM-1 is the receptor for rhinoviruses (the cause of most common colds) and malaria, and plays an inflammatory role in ocular allergies.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C527 |
| Product Size | 50 µg |
| Concentration | 0.5 mg/ml |
| Formulation | This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4. |
| Clone | YN1/1.7.4 |
| Target | CD54 |
| Applications | IHC FF, PhenoCycler® |
| Antigen | CD54 is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. |
| Storage | This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD54 |