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Anti-Mouse CD3ε (Clone 145-2C11) - Purified <i>in vivo </i>GOLD™ Functional Grade

Anti-Mouse CD3ε (Clone 145-2C11) - Purified <i>in vivo </i>GOLD™ Functional Grade (C1758-GRP)

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Description

CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# C1758
Concentration ≥ 5.0 mg/ml
Formulation This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Alternate Names Monoclonal Antibody CD3ε CD3 T3 145-2C11 CD3ε Mouse Anti-Mouse CD3ε Purified Low Endotoxin Functional Formulation Immunohistochemistry Immunoprecipitation Flow Cytometry Western Blotting Cell Depletion Blocking Immunofluorescence Apoptosis Cell Depletion Activation
Isotype IgG
Clone 145-2C11
Target CD3ε
Antibody Type Monoclonal
Applications Act, B, CyTOF®, Depletion, FA, FC, ICC, IF, IHC FF, in vivo, PhenoCycler®, WB
Antigen CD3ε is primarily expressed on mature T cells and NK-T cells and at different levels on differentiation-dependent thymocytes.
Storage Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Protein CD3ε