Anti-Mouse CD32/CD16 [Clone 2.4G2] - Purified (Fc Block)
Anti-Mouse CD32/CD16 [Clone 2.4G2] - Purified (Fc Block) (C247-GRP)
Products
Description
CD16 is expressed in two forms: CD16a and CD16b. CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. CD16b (FcγRIIIB) is a 48 kD GPI-anchored protein whose extracellular domain is over 95% homologous to that of CD16a. CD16 regulates both phagocytosis and antibody-dependent cell-mediated cytotoxicity. It has been reported that CD16 is involved in Natural Killer Cell activation and plays a role in signal transduction. The receptors, CD32 (FcγRIII) and CD16 (FcγRII), are 40-60 kD and bind antibody-antigen immune complexes and mediate adaptive immune responses.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C247 |
| Concentration | 0.5 mg/ml |
| Formulation | This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Isotype | IgG2b |
| Clone | 2.4G2 |
| Target | CD32/CD16 |
| Applications | B, FC, IHC FF, IP, PhenoCycler®, WB |
| Antigen | These receptors are present on B cells, monocyte/macrophages, NK cells, neutrophils, mast cells and dendritic cells. |
| Storage | This purified antibody is stable when stored at 2-8°C. Do not freeze. |
| Protein | CD32/CD16 |