Anti-Mouse CD278 (ICOS) - PE
Anti-Mouse CD278 (ICOS) - PE (C2263-GRP)
Products
Description
CD278 (ICOS) belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers (47-57kD) and enhances all basic T cell responses to a foreign antigen, specifically proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B cells. ICOS signaling is also an important regulator for T cell homeostasis. ICOS plays a role in humoral immune response and is thought to have involvement in the development of Th2 cells and to play a protective role in inflammatory autoimmune diseases.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C2263 |
| Concentration | 0.2 mg/ml |
| Formulation | This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody CD278 Inducible Costimulator 7E.17G9 ICOS Mouse Anti-Mouse CD278 (ICOS) - R-PE |
| Isotype | IgG2b |
| Clone | 7E.17G9 |
| Target | CD278 |
| Antibody Type | Monoclonal |
| Applications | FC |
| Antigen | ICOS is expressed on activated T cells and APCs including splenic B cells, dendritic cells, and macrophages. |
| Storage | This R-PE conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | CD278 |