Anti-Mouse CD252 (OX40L) [Clone RM134L] - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade
Anti-Mouse CD252 (OX40L) [Clone RM134L] - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade (C6336-GRP)
Products
Description
CD252 is a 35 kD member of the TNF superfamily and is the ligand for OX-40, which is primarily found on activated T cells. The CD252/OX-40 pair contributes to B-cell and T-cell interaction during the immune response. Both proliferative and IL-2 production responses of activated T cells are enhanced via OX-40 antigen stimulation, while proliferation and Ig secretion by activated B cells is enhanced via CD252 stimulation. Hence, because both T cells and B cells are activated in cross-linking, the CD252/OX-40 pair is considered reciprocally costimulatory.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C6336 |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Isotype | IgG2b κ |
| Clone | RM134L |
| Target | CD252 |
| Applications | B, FC, IHC FF, in vivo, WB |
| Antigen | CD252 is expressed on activated B cells and antigen presenting cells. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD252 |