Anti-Mouse CD25 - Purified <i>in vivo </i>GOLDâ„¢ Functional Grade
Anti-Mouse CD25 - Purified <i>in vivo </i>GOLDâ„¢ Functional Grade (C1194-GRP)
Products
Description
CD25, a 55 kD type I transmembrane glycoprotein, has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Many resting memory T cells constitutively express IL2RA. It functions as the receptor for HTLV-1, resulting in its expression on neoplastic cells in adult T cell lymphoma/leukemia. CD25 (sIL-2R) has been used to track disease progression. Some additional clinical applications include Chagas disease, a disease characterized by a decline of CD25 expression on immune cells, and Multiple sclerosis, in which treatments with mAbs target CD25.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C1194 |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Alternate Names | Monoclonal Antibody Interleukin-2 Receptor Alpha IL2RA IDDM10 CD25 IL2R TCGFR P55 Tac PC61 IL-2 Rα Mouse Anti-Mouse IL-2 Rα-Low Endotoxin Functional Formulation |
| Isotype | IgG1 λ |
| Clone | PC61 |
| Target | CD25 |
| Antibody Type | Monoclonal |
| Applications | B, Depletion, FA, FC, IHC FF, in vivo, IP, PhenoCycler®, WB |
| Antigen | CD25 is expressed in activated T cells and B cells, thymocyte subset, pre-B cells, T regulatory cells. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD25 |