Anti-Mouse CD152 (CTLA-4) - DyLight® 755
Anti-Mouse CD152 (CTLA-4) - DyLight® 755 (C1754-GRP)
Products
Description
CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C1754 |
| Concentration | 0.5 mg/ml |
| Formulation | This DyLight® 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. |
| Isotype | IgG |
| Clone | 9H10 |
| Target | CTLA-4 |
| Applications | FC |
| Antigen | CTLA-4 is expressed on activated T and B lymphocytes. |
| Storage | This DyLight® 755 conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | CTLA-4 |