Anti-Mouse CD137 (4-1BB) - Biotin
£525.00
Anti-Mouse CD137 (4-1BB) - Biotin (B561-50ug)
Product
| Cat # B561-50ug | Size 50 µg |
Price
£525.00
|
Qty
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Description
4-1BB (CD137) is a 39 kD transmembrane protein that is a member of the tumor necrosis factor (TNF) receptor family and is a co-stimulatory molecule that plays a role in T-cell-mediated proliferative response. When binding its ligand, CD137 provides costimulatory signals to both CD4 and CD8 T cells via the activation of NF-B, c-Jun and p38 downstream pathways. Crosslinking of CD137 boosts T cell proliferation, IL-2 secretion, survival and cytolytic activity. Furthermore, it can increase immune activity to eliminate tumors in mice. Agonistic anti-CD137 antibodies have been reported to stimulate a more intense immune system attack on cancers.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | B561 |
| Product Size | 50 µg |
| Alternate Names | 4-1BB 41BB 4 1BB Anti-Mouse 4-1BB-Biotin Antigen Aff. Pur. TNFRSF9 CD137 Antigen T-Cell Antigen ILA TNFRSF9 CD137 Antigen TCell Antigen ILA TNFRSF9 CD137 Antigen T Cell Antigen ILA Anti-Mouse 4-1BB-Biotin Antigen Aff. Pur. Polyclonal Antibody 4-1BB,TNFRSF9 CD137 Antigen T-Cell Antigen ILA Mouse Anti-Mouse 4-1BB-Biotin Antigen Aff. Pur. Polyclonal Antibody 41BB,TNFRSF9 CD137 Antigen TCell Antigen ILA Mouse AntiMouse 41BBBiotin Antigen Aff. Pur. Polyclonal Antibody 4 1BB,TNFRSF9 CD137 Antigen T Cell Antigen ILA Mouse Anti Mouse 4 1BB Biotin Antigen Aff. Pur. Anti-Mouse 4-1BB-Biotin Antigen Aff. Pur. |
| Target | 4-1BB |
| Antibody Type | Polyclonal |
| Applications | ELISA Det, FC, WB |
| Storage | -20°C to -70°C |