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Anti-Mouse CD127 (IL-7Rα) - Purified

£309.38

Anti-Mouse CD127 (IL-7Rα) - Purified (C2133-0.5mg)

Product

Cat #  C2133-0.5mg Size  0.5 mg Price 
£309.38
Qty 

Description

CD127 (IL7R-α) is a 60-90 kD type I cytokine receptor involved in the regulation of lymphopoiesis. The active receptor is an α/γ chain heterodimer. The common γ chain, which also associates with the IL-2 receptor, serves mainly to activate signal transduction via the IL7R complex. CD127 also interacts with the Thymic Stromal Lymphopoietin Receptor (TSLPR). CD127 determines signaling events via its association with cytoplasmic signaling molecules and has been reported to be a useful marker for identifying memory and effector T cells.

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# C2133
Product Size 0.5 mg
Concentration 0.5 mg/ml
Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Alternate Names Monoclonal Antibody CD127 IL-7Rα Interleukin-7 receptor alpha IL-7Rα chain CD127 Mouse Anti-Mouse CD127 (IL-7Rα) - Purified Flow Cytometry Immunoprecipitation Western Blotting Immunohistochemistry Immunofluorescence microscopy Immunology thymocytes IL-2 IL-4 IL-9 IL-13 IL-15
Isotype IgG2a κ
Clone A7R34
Target CD127
Antibody Type Monoclonal
Applications FA, FC, IF Staining, IHC FF, IP, WB
Antigen IL-7Rα is expressed on bone marrow lymphoid precursors, pro-B cells, monocytes/macrophages, NK-cells, naïve T cells, memory CD4+ and CD8+ T cells, intestinal colorectal and renal carcinoma cell lines, and keratinocytes.
Storage This purified antibody is stable when stored at 2-8°C. Do not freeze.
Protein CD127