Anti-Mouse CD127 (IL-7Rα) [Clone A7R34] - Purified <i>in vivo </i>GOLD™ Functional Grade
Anti-Mouse CD127 (IL-7Rα) [Clone A7R34] - Purified <i>in vivo </i>GOLD™ Functional Grade (C2223-GRP)
Products
Description
CD127 (IL7R-α) is a 60-90 kD type I cytokine receptor involved in the regulation of lymphopoiesis. The active receptor is an α/γ chain heterodimer. The common γ chain, which also associates with the IL-2 receptor, serves mainly to activate signal transduction via the IL7R complex. CD127 also interacts with the Thymic Stromal Lymphopoietin Receptor (TSLPR). CD127 determines signaling events via its association with cytoplasmic signaling molecules and has been reported to be a useful marker for identifying memory and effector T cells.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C2223 |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Alternate Names | Monoclonal Antibody CD127 IL-7Rα Interleukin-7 receptor alpha IL-7Rα chain A7R34 Mouse Anti-Mouse CD127 (IL-7Rα) - Purified Low Endotoxin Functional Formulation Flow Cytometry Immunoprecipitation Western Blotting Immunohistochemistry Immunology thymocytes IL-2 IL-4 IL-9 IL-13 IL-15 |
| Isotype | IgG2a κ |
| Clone | A7R34 |
| Target | CD127 |
| Antibody Type | Monoclonal |
| Applications | B, CyTOF®, FA, FC, IF Staining, IHC FF, in vivo, IP, WB |
| Antigen | IL-7Rα is expressed on bone marrow lymphoid precursors, pro-B cells, monocytes/macrophages, NK-cells, naïve T cells, memory CD4+ and CD8+ T cells, intestinal colorectal and renal carcinoma cell lines, and keratinocytes. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD127 |