Anti-Mouse/Rat CD126 (IL-6Rα) - Purified In vivo GOLD™ Functional Grade
Anti-Mouse/Rat CD126 (IL-6Rα) - Purified In vivo GOLD™ Functional Grade (I-1185-GRP)
Products
Description
CD126 (IL-6Rα) is an 80 kD type I cytokine receptor α chain that is a member of the Ig superfamily that can form a heterodimer with IL-6Rβ chain to form the high affinity IL-6 receptor. The IL-6/IL-6R complex is a potent pleiotropic cytokine that mediates cell growth and differentiation and has significant involvement in immune response. Inadequate production of IL-6 and IL-6R are thought to play a part in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-1185 |
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Alternate Names | Monoclonal Antibody CD126 IL-6 Receptor α chain IL-6R D7715A7 (15A7) Mouse CD126 Clone 15A7 15A7 Clone D7715A7 Flow Cytometry Blocking Immunoprecipitation Neutralization Biofunctional Assay Immunology Antibodies. anti-mouse CD126 |
| Isotype | IgG2b κ |
| Clone | D7715A7 (15A7) |
| Antibody Type | Monoclonal |
| Applications | FA, N, WB |
| Antigen | CD126 is expressed on activated T and B cells, monocytes, hepatocytes and plasma cells. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD126 |