Anti-Mouse CCL27 (Clone 68623)
Anti-Mouse CCL27 (Clone 68623) (C1452-GRP)
Products
Description
Chemokine (C-C motif) ligand 27 (CCL27) is a small cytokine belonging to the CC chemokine family. It is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediated inflammation of the skin. CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin. It elicits its chemotactic effects by binding to the chemokine receptor CCR10. CCL27 is one of the CC chemokines produced by epidermal keratinocytes and is suggested to be involved in the pathogenesis of inflammatory skin diseases. CCL27 modifies inflammation by attracting CCR10-positive and CCR4-positive cells into the lesional skin, and may participate in the pathogenesis of Th2-shifted skin diseases such as atopic dermatitis.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C1452 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Chemokine (C-C Motif) Ligand 27 ALP Eskine Cutaneous T-Cell Attracting Chemokine CTACK SCYA27 ILC skinkine PESKY 68623 CCL27 Mouse Anti-Mouse CCL27 |
| Isotype | IgG2b |
| Clone | 68623 |
| Target | CCL27 |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, N |
| Antigen | CCL27 is expressed by keratinocytes. |
| Storage | -20°C to -70°C |
| Protein | CCL27 |