LIG4 antibody
£227.50
LIG4 antibody (FNab04774)
Product
| Cat # FNab04774 | Size 100ug |
Price
£227.50
|
Qty
|
Description
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining(NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Specifications
| Manufacturer Cat# | FNab04774 |
|---|---|
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | ligase IV, DNA, ATP-dependent |
| Alternate Names | DNA ligase 4|DNA ligase IV|Polydeoxyribonucleotide synthase [ATP] 4|LIG4 |
| Calculated MW | 100-104 kDa |
| Protein ID | P49917 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Recommended dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Gene ID | 3981 |