Anti-K+/Cl- Cotransporter (KCC2) Antibody (11564)
£464.06
Anti-K+/Cl- Cotransporter (KCC2) Antibody (11564) (11564-100ug)
Product
| Cat # 11564-100ug | Size 100 µg |
Price
£464.06
|
Qty
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Description
KCC2 is a member of the cation-chloride cotransporter gene family. KCCs lower intracellular chloride concentrations below the electrochemical equilibrium potential. Depending on the concentration gradients of potassium and chloride, KCC2 can operate as a net efflux or influx pathway. KCC2 is expressed at high levels in neurons throughout the nervous system and is localized at inhibitory synapses of the spinal cord. Studies in mice have shown that KCC2 reduces GABA's inhibitory signaling resulting in motor defects, epilepsy, and anxiety-like behavior.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | 11564 |
| Product Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Formulation | PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. |
| Clone | S1-12 |
| Target | K+/Cl- Cotransporter (KCC2) |
| Applications | ICC, IF, IHC, IP, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. Avoid repeated freeze-thaw cycles. |
| Protein | K+/Cl- Cotransporter (KCC2) |