anti- ITM2C antibody
£262.50
anti- ITM2C antibody (FNab04419)
Product
| Cat # FNab04419 | Size 100µg |
Price
£262.50
|
Qty
|
Description
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation(By similarity).
Specifications
| Manufacturer | FineTest |
|---|---|
| Product Size | 100µg |
| Antibody Type | Monoclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Protein A+G purification |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Mouse |
| Isotype | IgG2a |
| Immunogen | integral membrane protein 2C |
| Alternate Names | BRI3 |
| Calculated MW | 35 kDa |
| Protein ID | Q9NQX7 |
| Clone | 5D9 |
| Reactivity | Human |
| Applications | ELISA, IF, WB |
| Recommended dilution | WB: 1:500-1:1000; IF: 1:20-1:200 |
| Gene ID | 81618 |