anti- ITM2C antibody

anti- ITM2C antibody

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation(By similarity).
Cat# Size Price Qty Buy
FNab04419 100µg £262.50

Additional Information

Property Value or Rating
Product Size 100µg
Manufacturer FineTest
Antibody Type monoclonal
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Physical Appearance liquid
Purification Protein A+G purification
Purity ≥95% as determined by SDS-PAGE
Host Mouse
Isotype IgG2a
Immunogen integral membrane protein 2C
Alternate Names BRI3
Calculated MW 35 kDa
Protein ID Q9NQX7
Clone 5D9
Reactivity Human
Applications ELISA, IF, WB
Recommended dilution WB: 1:500-1:1000; IF: 1:20-1:200
Gene ID 81618

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